佛罗里达大学招聘博士后研究DNA修复
药明康德/报道
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Description
The Caglayan lab in the Department of Biochemistry and Molecular Biology, University of Florida is accepting applications for multiple Postdoctoral Associate appointments. The NIH-funded research project will focus on studying genomic stability, oxidative stress-induced DNA damage processing, and DNA repair. For more information, please see the lab website at https://caglayan.biochem.med.ufl.edu
Job Description
Duties will include:
Supporting projects through original research, collaboration with other team members, interpreting and critically evaluating primary literature; collection and analysis of data; and maintaining a complete, accurate, and up-to-date lab notebook; preparing and editing manuscripts for publication as well as applications for grants; attending an annual meeting to disseminate research findings and progress; supervising and training of graduate students (PhD and Master’s level) and undergraduates. Applicants should have excellent communication and problem-solving skills and the ability to work flexible hours depending on specific experiments.
The Caglayan group is in both the Department of Biochemistry and Molecular Biology, and UF Health Cancer Center with investigators renowned for their contributions to the area of biochemistry and cancer biology. This exceptional training environment offers a highly supportive and collaborative scientific experience in many diverse areas of expertise.
Advertised Salary
The salary for this position is commensurate with experience as determined by NIH guidelines. Though the position is fully funded, the successful candidate will be mentored and encouraged to apply for additional financial support.
Select Publications
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Caglayan M. and Wilson S.H. Pol μ dGTP mismatch insertion opposite T coupled with ligation reveals a promutagenic DNA intermediate during double strand break repair. Nature Communications (2018) – in press
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Caglayan M., Prasad R., Krasich R., Longley M.J., Kadoda K., Tsuda M., Sasanuma H., Takeda S., Tano K., Copeland W.C., Wilson S.H. Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts. Nucleic Acids Research (2017) 17: 10079 – 10088.
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Caglayan M., Wilson S.H. Role of DNA polymerase β oxidized nucleotide insertion in DNA ligation failure. Journal of Radiation Research (2017) 1093: 1 – 5.
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Caglayan M., Horton J.K., Da-Peng D., Stefanick D.F., Wilson S.H. Oxidized nucleotide insertion by pol β confounds ligation during base excision repair. Nature Communications (2017) 8: 14045.
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Caglayan M., Wilson S.H. Oxidant and environmental toxicant-induced effects compromise DNA ligation during base excision DNA repair. DNA Repair (2015) 35: 85 – 89.
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Caglayan M., Horton J.K., Prasad R., Wilson S.H. Complementation of aprataxin deficiency by base excision repair enzymes. Nucleic Acids Research (2015) 43: 2271 – 2281.
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Caglayan M., Batra V.K., Sassa A., Prasad R., Wilson S.H. Role of polymerase β in complementing aprataxin deficiency during abasic-site base excision repair. Nature Structural and Molecular Biology (2014) 21: 497 – 499.
Qualifications
Minimum Requirements:
PhD, MD, or PhD/MD degree in a related discipline.
Preferred Qualifications:
The candidate should have experience in biochemistry, enzyme kinetics, protein purification. Previous working experience with evidence of experimental skills related to cell and molecular biology is preferred.
Application Instructions
To be considered for this position, please attach your Curriculum Vitae, a statement of research interest, and three (3) letters of recommendations or list of 3 references with contact information.
Review of applications will begin immediately and will continue until the position is filled.
Selected candidate will be required to provide an official transcript to the hiring department upon hire. A transcript will not be considered “official” if a designation of “Issued to Student” is visible. Degrees earned from an education institution outside of the United States are required to be evaluated by a professional credentialing service provider approval by National Association of Credential Evaluation Services (NACES), which can be found at http://naces.org/.
If an accommodation due to a di
sability is needed to apply for this position, please call 352-392-2477 or the Florida Relay System at 800-955-8771 (TDD). Hiring is contingent upon eligibility to work in the US. Searches are conducted in accordance with Florida’s Sunshine Law.
This position was originally posted under requisition # 507483. Previous applicants are still being considered and need not re-apply.
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